STRENGTH | MUSCLE – GENETICS | MUSCLE FIBER TYPE | SATELLITE CELLS | MUSCLE MEMORY


1 RESEARCH ARTICLE + 8 GRAPHICS – CLICK ON GRAPHIC TO ENLARGE


GENETICS & MUSCLE MASS | MUSCLE FIBER TYPE



SATELLITE CELLS


Nederveen, Phillips, Parise et al
INTRODUCTION & METHODS

– Muscle fibers change with regular resistance exercise; Satellite cells (SC) play an important role in muscle adaptation
– In untrained individuals, SC content and activation status increases after a single bout of exercise
– 16wk progressive resistance training (RT) program in 14 young (25±3yr) men
CONCLUSION
– Following RT, activation of SC in response to RT is accompanied by increases in muscle fiber capillarization

MUSCLE MEMORY


February 5 – 2018
AIM
– Assess muscle epigenetic responses and growth during:
1. Initial 7wks of hypertrophy training (loading)
2. During a subsequent 7wks of detraining (unloading)
3. During a subsequent 7wks of retraining (reloading)
RESULTS
– 6.5% increase in lean mass with the initial training (loading) then a return to baseline levels after 7 wks of detraining (unloading)
– During the subsequent 7wks of retraining (reloading), the muscular growth response was almost 100% greater than the initial training/loading period
– Also, researchers showed increased expression and hypomethylation of key genes following intitial loading which can explain in part the initial growth
– These epigenetic responses were significantly enhanced (just like muscle growth) during reloading, indicating a genetic “memory” of earlier encounters of muscle hypertrophy (as in this case, during the initial 7-week loading)

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