HEALTH – T2 DIABETES – EXERCISE


2 RESEARCH ARTICLES


REMISSION OF RECENTLY DIAGNOSED T2D MELLITUS WITH WEIGHT LOSS & EXERCISE – 2015


Ades PA1, Savage PD, Marney AM, Harvey J, Evans KA
PURPOSE
– Determine rate of remission of recently diagnosed (<1 yr) type 2 diabetes mellitus (T2DM) in overweight/obese individuals, with a 6-month program of weight loss and exercise
METHODS
– Subjects (N=12) were overweight/obese (BMI=35.8±4.3 kg/m), sedentary, unfit (Vo2peak=20.7 ± 4.7 mL·kg·min) and recently (<1 yr) diagnosed with T2DM
– They were willing to participate in a lifestyle program of behavioral weight loss counseling and supervised exercise located at a cardiac rehabilitation program prior to consideration of diabetes medications
– Glycated hemoglobin (HbA1c) level before and after the study intervention was the primary study outcome, along with secondary metabolic, fitness, and body composition variables
RESULTS
(1) Subjects had a baseline HbA1c of 6.5% to 8.0% (mean 6.8 ± 0.2). Subjects lost 9.7 ± 0.2 kg body weight (9%) and improved peak aerobic capacity by 18%
(2) Two subjects withdrew for medical reasons unrelated to the lifestyle program
(3) Eight of 10 completers (80%) went into partial T2DM remission, with the mean HbA1c decreasing from 6.8 ± 0.2% to 6.2 ± 0.3%
CONCLUSIONS
– For individuals with recently diagnosed T2DM willing to undertake a formal lifestyle program, 80% of study completers and 67% of our total population achieved at least a partial T2DM remission at 6 months


EXERCISE AND GLUCOSE CONTROL – 2014


Buresh R. J Sports Med Phys Fitness
– The American Diabetes Association recommends regular exercise and maintenance of healthy body weight as important in prevention of T2DM, and exercise is also a cornerstone of treatment regimens for persons already diagnosed with T2DM
– With T2DM, the capacity of muscle contraction to stimulate glucose uptake in a manner that is independent of insulin establishes exercise as a powerful “medicine” in its treatment.
– Exercise, therefore, serves an important role in prevention and treatment of T2DM


 

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