HEALTH – T2 DIABETES – STRENGTH & ENDURANCE TRAINING


3 RESEARCH ARTICLES


EFFECTS OF COMBINED AEROBIC-RESISTANCE EXERCISE ON GLYCEMIC CONTROL – 2015


Tomas-Carus P1, Ortega-Alonso A, Pietiläinen KH, Santos V, Gonçalves G, H H, Ramos J, Raimundo A.
AIM
Evaluate effects of 12-wks combined aerobic-resistance exercise therapy on fatigue and isokinetic muscle strength, glycemic control and health-related quality of life (HRQoL) in moderately affected type 2 diabetes (T2DM) patients
METHODS
– A randomized controlled trial design was employed. 43 T2DM patients were assigned to:
(1) Exercise group (n = 22), performing 3 weekly sessions of 60 minutes of combined aerobic resistance exercise for 12-wks
(2) No exercise control group (n = 21)
– Both groups were evaluated at a baseline and after 12-wks of exercise therapy for:
(1) muscle strength and fatigue by isokinetic dynamometry
(2) plasma glycated hemoglobin A1C (HbA1C)
(3) HRQoL utilizing the SF–36 questionnaire.
RESULTS
(1) The exercise therapy led to improvements in muscle fatigue in knee extensors (+55%) and increased muscle strength in knee flexors and extensors (+15 to +30%), while HbA1C decreased (-18%)
(2) The exercising patients showed sizeable improvements in HRQoL: physical function (+53%), vitality (+21%) and mental health (+40%)
CONCLUSION
– 12-wks of combined aerobic-resistance exercise was highly effective to improve muscle strength and fatigue, glycemic control and several aspects of HRQoL in T2DM patients
– These data encourage the use of aerobic and resistance exercise in the good clinical care of T2DM


REMISSION OF RECENTLY DIAGNOSED T2D MELLITUS WITH WEIGHT LOSS & EXERCISE – 2015


Ades PA1, Savage PD, Marney AM, Harvey J, Evans KA
PURPOSE
– Determine rate of remission of recently diagnosed (<1 yr) type 2 diabetes mellitus (T2DM) in overweight/obese individuals, with a 6-month program of weight loss and exercise
METHODS
– Subjects (N=12) were overweight/obese (BMI=35.8±4.3 kg/m), sedentary, unfit (Vo2peak=20.7 ± 4.7 mL·kg·min) and recently (<1 yr) diagnosed with T2DM
– They were willing to participate in a lifestyle program of behavioral weight loss counseling and supervised exercise located at a cardiac rehabilitation program prior to consideration of diabetes medications
– Glycated hemoglobin (HbA1c) level before and after the study intervention was the primary study outcome, along with secondary metabolic, fitness, and body composition variables
RESULTS
(1) Subjects had a baseline HbA1c of 6.5% to 8.0% (mean 6.8 ± 0.2). Subjects lost 9.7 ± 0.2 kg body weight (9%) and improved peak aerobic capacity by 18%
(2) Two subjects withdrew for medical reasons unrelated to the lifestyle program
(3) Eight of 10 completers (80%) went into partial T2DM remission, with the mean HbA1c decreasing from 6.8 ± 0.2% to 6.2 ± 0.3%
CONCLUSIONS
– For individuals with recently diagnosed T2DM willing to undertake a formal lifestyle program, 80% of study completers and 67% of our total population achieved at least a partial T2DM remission at 6 months


EXERCISE AND GLUCOSE CONTROL – 2014


Buresh R. J Sports Med Phys Fitness
– The American Diabetes Association recommends regular exercise and maintenance of healthy body weight as important in prevention of T2DM, and exercise is also a cornerstone of treatment regimens for persons already diagnosed with T2DM
– With T2DM, the capacity of muscle contraction to stimulate glucose uptake in a manner that is independent of insulin establishes exercise as a powerful “medicine” in its treatment.
– Exercise, therefore, serves an important role in prevention and treatment of T2DM


 

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