NUTRITION – LEUCINE – BED REST or INACTIVITY – AGING


2 RESEARCH ARTICLES


PROTECTING SKELETAL MUSCLE PROTEIN & AMINO ACID DURING PERIODS OF DISUSE – 2016


Elfego Galvan 1, Emily Arentson-Lantz 1,2, Séverine Lamon 3 and Douglas Paddon-Jones
INTRODUCTION
– Leucine protects skeletal muscle by mitigating the loss of muscle mass, strength, and endurance associated with disuse


LEUCINE PARTIALLY PROTECTS MUSCLE MASS & FUNCTION DURING BED REST IN MIDDLE-AGED ADULTS – 2015


Kirk L English, Douglas Paddon-Jones et al
OBJECTIVE:
– Determine whether leucine can protect skeletal muscle health during bed rest
DESIGN:
– Adults (n = 19; age: 52 ± 1 y)
(a) leucine supplementation (LEU group: 0.06 g ∙ kg(-1) ∙ meal(-1))
(b) an alanine control (CON group)
– during 14 d of bed rest
CONCLUSIONS:
(1) Bed rest has a negative effect on muscle metabolism, mass, and function in middle-aged adults
(2) Leucine supplementation may partially protect muscle health during relatively brief periods of physical inactivity


 

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