2 RESEARCH ARTICLES
Amy Jennings3, Alex MacGregor3, Ailsa Welch3, Phil Chowienczyk4,Tim Spector4, and Aedín Cassidy3,*
– Although data suggest total protein, and specific amino acids (AAs) reduces blood pressure, data on other cardiovascular disease risk factors are limited
– Examine associations between AAs with known mechanistic links to cardiovascular health and direct measures of arterial stiffness, central blood pressure, atherosclerosis
(1) 1898 female twins aged 18–75 y
(1) Data suggest that intake of several AAs is associated with cardiovascular benefits beyond blood pressure reduction in healthy women
(2) The magnitude of the observed associations was similar to those previously reported for other lifestyle factors
(3) Increasing intake of these AAs could be an important and readily achievable way to reduce cardiovascular disease risk
Tielemans SM1, Altorf-van der Kuil W, Engberink MF, Brink EJ, van Baak MA, Bakker SJ, Geleijnse JM.
– There is growing evidence from epidemiological studies that dietary protein may beneficially influence blood pressure (BP)
(1) We performed a meta-analysis of 29 observational studies and randomized controlled trials (RCTs)
(2) The analysis included eight cross-sectional studies (n=48 985), four prospective studies (n=11 761) and 17 RCTs (n=1449).
(1) These findings suggest that increasing intake of protein at the expense of carbohydrates may have a beneficial effect on BP
(2) The BP effect of specific types of protein remains to be established.